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Fig. 1 | Parasites & Vectors

Fig. 1

From: Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model

Fig. 1

rSj16 protein and Sj16 peptide alleviated hepatic granuloma in S. japonicum infected mice. a The experiment flow chart. Infected BALB/c mice were respectively injected with PBS, GST protein (50 µg/d), rSj16 (50 µg/d), Sj16 peptide (50 µg/d) for 7 consecutive days before the animals sacrificed at 6, 8 and 10 weeks post-infection. b H&E staining of representative hepatic granulomas. Scale-bars: 100 μm. c Size of liver granulomas. Results are expressed as the mean ± SEM of 4–5 mice per group. *P < 0.05, **P < 0.01, ***P < 0.001, compared with the PBS group; ##P < 0.01, ###P < 0.001, compared with the GST group; &P < 0.05, the rSj16 group compared with Sj16 peptide group. Similar results were obtained in two repeat experiments

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Parasites & Vectors

ISSN: 1756-3305

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