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Table 1 Total worm counts, means and percent reduction relative to placebo for dogs treated orally with combination product tablets 30 days after experimental infection with Dirofilaria immitis (ZoeKY-2013, Laboratory Study 1)

From: Laboratory and field studies to investigate the efficacy of a novel, orally administered combination product containing moxidectin, sarolaner and pyrantel for the prevention of heartworm disease (Dirofilaria immitis) in dogs

 Treatment
PlaceboMoxidectin/Sarolaner/Pyrantel combination product
Total worm counts for individual dogs320
320
320
360
200
370
330
270
Range20–370–0
Arithmetic mean31.10
% reduction100
Geometric mean30.70
% reduction100
P-value< 0.0001