Table 2 Total worm counts, means and percent reduction relative to placebo for dogs treated orally with combination product, sarolaner-alone or moxidectin-alone tablets 30 days after experimental infection with Dirofilaria immitis (GCFL-01-2014, Laboratory Study 2)

Total worm counts for individual dogs

39

37

0

0

42

33

0

0

44

32

0

0

41

40

0

0

39

39

0

0

40

38

0

0

40

38

0

0

35

37

0

0

Range

35–44

32–40

0–0

0–0

Arithmetic mean

40.0

36.8

0

0

% Reduction

–

8.1

100

100

Geometric mean

39.9

36.7

0

0

% Reduction

–

8.2

100

100

P-value vs placebo

–

0.0026

< 0.0001

< 0.0001

P-value vs sarolaner

–

–

< 0.0001

< 0.0001

P-value vs moxidectin

–

–

–

1.0