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Table 5 Test results from a clinical field study investigating the efficacy and safety of combination product chewable tablets administered orally once a month for 11 months for the prevention of heartworm disease in the USA

From: Laboratory and field studies to investigate the efficacy of a novel, orally administered combination product containing moxidectin, sarolaner and pyrantel for the prevention of heartworm disease (Dirofilaria immitis) in dogs

Treatment groupStudy dayAdult HW antigen testMicrofilaria test
NegativePositiveNegativePositive
No. of dogs%No. of dogs%No. of dogs%No. of dogs%
Moxidectin/Sarolaner/Pyrantel combination product3302461000024610000
Heartgard® Plus33011798.321.711899.210.8