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Table 5 Test results from a clinical field study investigating the efficacy and safety of combination product chewable tablets administered orally once a month for 11 months for the prevention of heartworm disease in the USA

From: Laboratory and field studies to investigate the efficacy of a novel, orally administered combination product containing moxidectin, sarolaner and pyrantel for the prevention of heartworm disease (Dirofilaria immitis) in dogs

Treatment group

Study day

Adult HW antigen test

Microfilaria test

Negative

Positive

Negative

Positive

No. of dogs

%

No. of dogs

%

No. of dogs

%

No. of dogs

%

Moxidectin/Sarolaner/Pyrantel combination product

330

246

100

0

0

246

100

0

0

Heartgard® Plus

330

117

98.3

2

1.7

118

99.2

1

0.8