Fig. 2

Caspase-1 activation in S. japonicum-infected HSCs. a The expression of caspase-1 in HSCs isolated from mice 6 weeks post-infection with S. japonicum infection was evaluated by qPCR. b The expression of caspase-1 protein in HSCs isolated from mice 6 weeks post-infection with S. japonicum infection was assayed by Western blot analysis. c Representative confocal fluorescence images of the localization of caspase-1 with α-SMA in HSCs isolated from mice 6 weeks post S. japonicum-infection and the results of co-localization efficiency analysis (n = 5). Scale bar, 20 μm. *P < 0.05, ***P < 0.001