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Table 2 Correlation between trachoma clinical signs and ocular C. trachomatis infection as detected by Amplicor in children aged 0–9 years

From: Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating strains in The Gambia and Senegal

Study No. of children examined No. of children with TF (%) [95% CI]a No. of children with TI (%) [95% CI]a No. of infected children (%) [95% CI]a No. of children with TF who were infected (%) [95% CI]a No. of infected children who had TF (%) [95% CI]a No. of children with TI who were infected (%) [95% CI]a No. of infected children who had TI (%) [95% CI]a No. of children with active trachoma who were infected (%) [95% CI]a No. of infected children who had active trachoma (%) [95% CI]a
Gambia baseline 1171 280 (23.9) [21.5–26.5] 2 (0.2) [0.02–0.6]c 35 (3.0) [2.1–4.] 24/280 (8.6) [5.6–12.5] 24/35 (68.6) [50.7–83.1] 0/2 (0) [0–84.2 b] 0/35 (0) [0–100.0 b] 24/280 (8.6) [5.6–12.5] 24/35 (68.6) [50.7–83.1]
Senegal baseline 1613 216 (13.4) [11.8–15.2] 38 (2.4) [1.7–3.2]d 29 (1.8) [1.2–2.6] 24/216 (11.1) [7.3–16.1] 24/29 (82.8) [64.2–94.2] 4/38 (10.5) [2.9–24.8] 4/29 (13.8) [3.9–31.7] 24/240 (10.0) [6.5–14.5] 24/29 (82.8) [64.2–94.2]
Gambia FU 1171 202 (17.3) [15.1–19.5] 8 (0.7) [0.3–1.3]e 45 (3.8) [2.8–5.1] 29/202 (14.4) [9.8–20.0] 29/45 (64.4) [48.8–78.1] 3/8 (37.5) [8.5–75.5] 3/45 (6.7) [1.4–18.3] 29/207 (14.0) [9.6–19.5] 29/45 (64.4) [48.8–78.1]
Senegal FU 1771 135 (7.6) [6.4–9.0] 18 (1.0) [0.6–1.6]f 64 (3.6) [2.8–4.6] 39/135 (28.9) [21.4–37.3] 39/64 (60.9) [47.9–72.9] 6/18 (33.3) [13.3–59.0] 6/64 (9.4) [3.5–19.3] 39/142 (27.5) [20.3–35.6] 39/64 (60.9) [47.9–72.9]
  1. a95% confidence interval
  2. bOne-sided, 97.5% confidence interval
  3. cBoth children also had TF
  4. d14 of these children also had TF
  5. eThree of these children also had TF
  6. f11 of these children also had TF