Table 2 Correlation between trachoma clinical signs and ocular C. trachomatis infection as detected by Amplicor in children aged 0–9 years
Study | No. of children examined | No. of children with TF (%) [95% CI]a | No. of children with TI (%) [95% CI]a | No. of infected children (%) [95% CI]a | No. of children with TF who were infected (%) [95% CI]a | No. of infected children who had TF (%) [95% CI]a | No. of children with TI who were infected (%) [95% CI]a | No. of infected children who had TI (%) [95% CI]a | No. of children with active trachoma who were infected (%) [95% CI]a | No. of infected children who had active trachoma (%) [95% CI]a |
|---|---|---|---|---|---|---|---|---|---|---|
Gambia baseline | 1171 | 280 (23.9) [21.5–26.5] | 2 (0.2) [0.02–0.6]c | 35 (3.0) [2.1–4.] | 24/280 (8.6) [5.6–12.5] | 24/35 (68.6) [50.7–83.1] | 0/2 (0) [0–84.2 b] | 0/35 (0) [0–100.0 b] | 24/280 (8.6) [5.6–12.5] | 24/35 (68.6) [50.7–83.1] |
Senegal baseline | 1613 | 216 (13.4) [11.8–15.2] | 38 (2.4) [1.7–3.2]d | 29 (1.8) [1.2–2.6] | 24/216 (11.1) [7.3–16.1] | 24/29 (82.8) [64.2–94.2] | 4/38 (10.5) [2.9–24.8] | 4/29 (13.8) [3.9–31.7] | 24/240 (10.0) [6.5–14.5] | 24/29 (82.8) [64.2–94.2] |
Gambia FU | 1171 | 202 (17.3) [15.1–19.5] | 8 (0.7) [0.3–1.3]e | 45 (3.8) [2.8–5.1] | 29/202 (14.4) [9.8–20.0] | 29/45 (64.4) [48.8–78.1] | 3/8 (37.5) [8.5–75.5] | 3/45 (6.7) [1.4–18.3] | 29/207 (14.0) [9.6–19.5] | 29/45 (64.4) [48.8–78.1] |
Senegal FU | 1771 | 135 (7.6) [6.4–9.0] | 18 (1.0) [0.6–1.6]f | 64 (3.6) [2.8–4.6] | 39/135 (28.9) [21.4–37.3] | 39/64 (60.9) [47.9–72.9] | 6/18 (33.3) [13.3–59.0] | 6/64 (9.4) [3.5–19.3] | 39/142 (27.5) [20.3–35.6] | 39/64 (60.9) [47.9–72.9] |