Fig. 3

Antischistosomal activity as a function of disease set in the Pathogen Box. The Pathogen Box contains compounds for which activity against various micro-organisms had been previously determined during the assembly of the collection (disease sets). For each compound (represented as a circle), the normalized median activity score at 72 h was calculated and plotted as a function of disease. A grey circle indicates that a median activity score of < 0.5 was attributed by all of the screening centers, whereas green, blue and red circles indicate that a score ≥ 0.5 was attributed by one, two or all three centers, respectively