Table 1 Geometric (arithmetic) mean live H. longicornis counts and ranges for dogs treated once orally (Day 0) with placebo or sarolaner chewable tables at 2 mg/kg and percent efficacy relative to placebo at 48 h after treatment and subsequent weekly re-infestations

2

4.4 (4.6)

2–7

8/8

0.0^a (0.0)

0–0

0/8

100 (100)

7

15.5 (15.6)

13–21

8/8

0.0^a (0.0)

0–0

0/8

100 (100)

14

18.3 (18.5)

14–23

8/8

0.0^a (0.0)

0–0

0/8

100 (100)

21

18.8 (19.9)

13–32

8/8

0.0^a (0.0)

0–0

0/8

100 (100)

28

20.7 (21.1)

13–24

8/8

0.2^a (0.3)

0–1

2/7

98.9 (98.7)

35

23.9 (24.1)

20–30

8/8

0.6^a (1.0)

0–4

3/7

97.4 (95.9)