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Table 1 Geometric (arithmetic) mean live H. longicornis counts and ranges for dogs treated once orally (Day 0) with placebo or sarolaner chewable tables at 2 mg/kg and percent efficacy relative to placebo at 48 h after treatment and subsequent weekly re-infestations

From: Efficacy of sarolaner (Simparica®) against induced infestations of Haemaphysalis longicornis on dogs

Day Placebo Sarolaner % Efficacy
Mean Range Dogs with ticks Mean Range Dogs with ticks
2 4.4 (4.6) 2–7 8/8 0.0a (0.0) 0–0 0/8 100 (100)
7 15.5 (15.6) 13–21 8/8 0.0a (0.0) 0–0 0/8 100 (100)
14 18.3 (18.5) 14–23 8/8 0.0a (0.0) 0–0 0/8 100 (100)
21 18.8 (19.9) 13–32 8/8 0.0a (0.0) 0–0 0/8 100 (100)
28 20.7 (21.1) 13–24 8/8 0.2a (0.3) 0–1 2/7 98.9 (98.7)
35 23.9 (24.1) 20–30 8/8 0.6a (1.0) 0–4 3/7 97.4 (95.9)
  1. aGeometric mean live tick count significantly lower than placebo (11.62 ≤ t(df) ≤ 59.99, where 13.0 ≤ df ≤ 14.1, P < 0.0001)