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Table 4 Partial of upregulated DEGs in the high throughput sequencing data

From: Transcriptomic analysis of reproductive damage in the epididymis of male Kunming mice induced by chronic infection of Toxoplasma gondii PRU strain

SymbolNamelog2(FC)Function
Iigp1Interferon-inducible GTPase 16.5608Required for disruption of the parasitophorous vacuole formed following T. gondii infection and subsequent killing of the parasite
Klrb1cKiller cell lectin-like receptor subfamily B member 1C6.17868Plays a stimulatory role on natural killer (NK) cells cytotoxicity, activation by cross-linking of the receptor induces Ca2+ mobilization and interferon-gamma production
Tgtp1T cell-specific GTPase 15.61362Involved in innate cell-autonomous resistance to intracellular pathogens, such as T. gondii
Tnfsf10Tumor necrosis factor (ligand) superfamily, member 101.53097Involved in male gonad development and regulation of the apoptotic process
Spata18Spermatogenesis associated 181.29567A key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage
Pgk2Phosphoglycerate kinase 21.11099Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis
Piwil2Piwi-like RNA-mediated gene silencing 21.1907Essential role in meiotic differentiation of spermatocytes and self-renewal of spermatogonial stem cells