Table 1 The chemical nomenclature, class, empirical formula, molar mass and solvent of ion transport inhibitors tested against A. castellanii

Gadolunium (III) chloride anhydrous

Cation channel inhibitor

GdCl₃

263.61

Water

Strontium chloride anhydrous

Calcium channel inhibitor

SrCl₂

158.52

Ethanol

CLP257

(5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone

Potassium chloride cotransporter

C₁₄H₁₄FN₃O₂S

307.34

DMSO 20 mg/ml

Tenatoprazole

(RS)-3-Methoxy-8-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-2,7,9-triazabicyclo[4.3.0]nona-2,4,8,10-tetraene

Proton pump inhibitor

C₁₆H₁₈N₄O₃S

346.40

DMSO 5 mg/ml

PF-03716556

PF-03716556, [N-(2-Hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide]

Acid pump inhibitor

C₂₂H₂₆N₄O₃

394.47

DMSO ≥10 mg/ml

3′,4′-dichlorobenzamil hydrochloride

L-594,881

Sodium–calcium exchanger inhibitor

C₁₃H₁₂N₇OCl₃

HCl

425.10

DMSO 30 mg/ml

Stevioside hydrate

(4α-13-[(2-O-β-d-Glucopyranosyl-β-d-glucopyranosyl)oxy]kaur-16-en-18-oic acid β-d-glucopyranosyl ester

Potassium channel

C₃₈H₆₀O₁₈

xH₂O

804.87 (anhydrous basis)

DMSO 25 mg/ml

Cariporide

HOE-642, N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide, N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide

Sodium–hydrogen exchanger inhibitor

C₁₂H₁₇N₃O₃S

283.35

DMSO 20 mg/ml

Lanthanum oxide

Potassium channel

La₂O₃

325.808

Dilute nitric acid