Fig. 7

CD226 and TIGIT expression on lymphocytes of P. berghei ANKA-infected mice, with or without α-lactose treatment. The mice were sacrificed on 15 day p.i., and circulatory immune cells were obtained and analyzed using flow cytometry. a Histograms showing the proportion of CD226⁺ cells within the CD3⁺CD4⁻, CD3⁺CD4⁺, and CD3⁻CD49b⁺ cell populations among the four groups. b Histograms showing the proportion of TIGIT⁺ cells within the CD3⁺CD4⁻, CD3⁺CD4⁺, and CD3⁻CD49b⁺ cell populations among the four groups. The results are representative of three independent experiments with five to seven mice in each group per experiment, with data denoting means ± SDs. *^{, $} P <0.05, **^{, $$, &&} P <0.01, ***P < 0.001. *^(black) indicates comparisons with the control group and control-α-lac group. *^(red) indicates comparisons with the control group. *^(blue) indicates comparisons with the control-α-lac group. ^$ indicates comparisons with the PbA group, and ^& indicates the comparisons with the control group