Toll-like receptors 2, 4 and 7, interferon-gamma and interleukin 10, and programmed death ligand 1 transcripts in skin from dogs of different clinical stages of leishmaniosis

Table 3 Multiple logistic regression models performed with all data available that presented statistical significance

	Variables	Coefficient (β)	SE	χ²	P-value	Odds ratio	95% CI
All dogs (clinically-lesioned vs normal-looking skin) (n = 35)	Intercept	− 1.99	0.52
	TLR2 transcript	0.240	0.060	6.790	0.009*	1.29	0.62–2.73
	IFN-γ transcript	0.003	0.001	4.570	0.033*	1.07	0.52–2.23
Group B (clinically-lesioned vs normal-looking skin) (n = 14)	Intercept	− 1.150	0.910
	TLR2 transcript	0.300	0.150	4.120	0.042*	1.34	0.47–3.82
	IL-10 transcript	− 0.260	0.160	2.790	0.095	0.78	0.26–2.15
	IFN-γ transcript	0.003	0.002	3.230	0.072	1.00	0.35–2.85
	PD-L1 transcript	0.160	0.110	2.190	0.139	1.16	0.40–3.29

Notes: Coefficient is the mathematical weightings of the explanatory variables in the equation. Intercept is a mathematical constant of the model (no clinical interpretation)
Abbreviations: CI, confidence interval; SE, standard error; group B, stage II-III-severely affected dogs
*P < 0.05

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