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Table 2 Distribution of ERR and CR among the study population and by infection intensity

From: Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

  Egg reduction rate (ERR) Cure rate (CR)
Post dose 1 Post-dose 3 P-valuec Post-dose 1 Post-dose 3 P-valuec
e/Ea % P-value e/Ea % P-value   n/Nb % P-value n/Nb % P-value  
Study population 309/4369 92.9   408/7953 94.9 0.003 52/67 77.6   72/82 87.8 0.15
Age    < 0.0001    < 0.0001 < 0.0001    0.95d    0.91 0.78
 6–8 5/313 98.4   7/2017 99.7    10/12 83.3   13/15 86.7   
 9–11 69/1727 96.0   70/2739 97.4    19/25 76.0   24/27 92.0   
 12–14 223/1420 84.3   99/1514 93.5    16/21 76.2   21/25 88.9   
 15–23 12/909 98.7   232/1683 86.2    7/9 77.8   14/15 93.3   
Gender    < 0.0001    < 0.0001 < 0.0001    0.058    0.09 0.007
 Female 7/1914 99.6   41/4602 99.1    27/30 90.0   39/41 95.1   
 Male 302/2455 87.7   367/3351 89.0    25/37 67.6   33/41 80.5   
Location       0.020         
 Bindo 0/1 100   38/512 92.6    1/1 100   3/4 75.0   
 Zilé-PK 309/4368 92.9   370/7441 95.0   0.0001 51/66 77.3   69/78 88.5   0.12
Infection intensity    < 0.0001    < 0.0001 < 0.0001    0.01d    0.004d < 0.0001
 Light 57/519 89.0   2/566 99.6    40/46 87.0   45/46 97.8   
 Heavy 252/3850 93.5   406/7387 94.5    12/21 57.1   27/36 75.0   
  1. aE is the total Schistosoma egg counts at baseline and e is the total Schistosoma egg counts at control
  2. bN is the number of participants treated at baseline and n is the number of participants found negative at control
  3. cP-value to assess the significant difference observed between post-dose 1 and post-dose 3 results
  4. dFisher’s exact test applied
  5. Note: The ERR and CR was assessed at PZQ post-dose1 (n = 67) and post-dose 3 (n = 82)