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Table 2 Distribution of ERR and CR among the study population and by infection intensity

From: Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

 Egg reduction rate (ERR)Cure rate (CR)
Post dose 1Post-dose 3P-valuecPost-dose 1Post-dose 3P-valuec
e/Ea%P-valuee/Ea%P-value n/Nb%P-valuen/Nb%P-value 
Study population309/436992.9 408/795394.90.00352/6777.6 72/8287.80.15
Age  < 0.0001  < 0.0001< 0.0001  0.95d  0.910.78
 6–85/31398.4 7/201799.7  10/1283.3 13/1586.7  
 9–1169/172796.0 70/273997.4  19/2576.0 24/2792.0  
 12–14223/142084.3 99/151493.5  16/2176.2 21/2588.9  
 15–2312/90998.7 232/168386.2  7/977.8 14/1593.3  
Gender  < 0.0001  < 0.0001< 0.0001  0.058  0.090.007
 Female7/191499.6 41/460299.1  27/3090.0 39/4195.1  
 Male302/245587.7 367/335189.0  25/3767.6 33/4180.5  
Location     0.020        
 Bindo0/1100 38/51292.6  1/1100 3/475.0  
 Zilé-PK309/436892.9 370/744195.0 0.000151/6677.3 69/7888.5 0.12
Infection intensity  < 0.0001  < 0.0001< 0.0001  0.01d  0.004d< 0.0001
 Light57/51989.0 2/56699.6  40/4687.0 45/4697.8  
 Heavy252/385093.5 406/738794.5  12/2157.1 27/3675.0  
  1. aE is the total Schistosoma egg counts at baseline and e is the total Schistosoma egg counts at control
  2. bN is the number of participants treated at baseline and n is the number of participants found negative at control
  3. cP-value to assess the significant difference observed between post-dose 1 and post-dose 3 results
  4. dFisher’s exact test applied
  5. Note: The ERR and CR was assessed at PZQ post-dose1 (n = 67) and post-dose 3 (n = 82)