Table 2 Distribution of ERR and CR among the study population and by infection intensity
Egg reduction rate (ERR) | Cure rate (CR) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Post dose 1 | Post-dose 3 | P-valuec | Post-dose 1 | Post-dose 3 | P-valuec | |||||||||
e/Ea | % | P-value | e/Ea | % | P-value | n/Nb | % | P-value | n/Nb | % | P-value | |||
Study population | 309/4369 | 92.9 | 408/7953 | 94.9 | – | 0.003 | 52/67 | 77.6 | 72/82 | 87.8 | – | 0.15 | ||
Age | < 0.0001 | < 0.0001 | < 0.0001 | 0.95d | 0.91 | 0.78 | ||||||||
6–8 | 5/313 | 98.4 | 7/2017 | 99.7 | 10/12 | 83.3 | 13/15 | 86.7 | ||||||
9–11 | 69/1727 | 96.0 | 70/2739 | 97.4 | 19/25 | 76.0 | 24/27 | 92.0 | ||||||
12–14 | 223/1420 | 84.3 | 99/1514 | 93.5 | 16/21 | 76.2 | 21/25 | 88.9 | ||||||
15–23 | 12/909 | 98.7 | 232/1683 | 86.2 | 7/9 | 77.8 | 14/15 | 93.3 | ||||||
Gender | < 0.0001 | < 0.0001 | < 0.0001 | 0.058 | 0.09 | 0.007 | ||||||||
Female | 7/1914 | 99.6 | 41/4602 | 99.1 | 27/30 | 90.0 | 39/41 | 95.1 | ||||||
Male | 302/2455 | 87.7 | 367/3351 | 89.0 | 25/37 | 67.6 | 33/41 | 80.5 | ||||||
Location | 0.020 | |||||||||||||
Bindo | 0/1 | 100 | 38/512 | 92.6 | 1/1 | 100 | 3/4 | 75.0 | ||||||
Zilé-PK | 309/4368 | 92.9 | 370/7441 | 95.0 | 0.0001 | 51/66 | 77.3 | 69/78 | 88.5 | 0.12 | ||||
Infection intensity | < 0.0001 | < 0.0001 | < 0.0001 | 0.01d | 0.004d | < 0.0001 | ||||||||
Light | 57/519 | 89.0 | 2/566 | 99.6 | 40/46 | 87.0 | 45/46 | 97.8 | ||||||
Heavy | 252/3850 | 93.5 | 406/7387 | 94.5 | 12/21 | 57.1 | 27/36 | 75.0 | ||||||