Genetic and antigenic variation of the bovine tick-borne pathogen Theileria parva in the Great Lakes region of Central Africa

Table 4 Pairwise estimates of genetic distance among nine T. parva populations using F_ST statistic for nucleotide sequences of Tp2

Country	Population	DRC AEZ1	DRC AEZ2	DRC AEZ3	Burundi AEZ1	BA	BD	CD	South Sudan	LS
DRC	DRC AEZ1	–	0.008	< 0.001	0.2	< 0.001	0.001	0.4	< 0.001	0.4
	DRC AEZ2	0.17	–	< 0.001	0.06	< 0.001	0.004	< 0.001	< 0.001	0.07
	DRC AEZ3	0.20	0.58	–	< 0.001	< 0.001	< 0.001	0.04	0.3	< 0.001
Burundi	Burundi AEZ1	0.02	0.08	0.3	–	< 0.001	0.008	0.1	< 0.001	0.3
Kenya	BA	0.17	0.19	0.39	0.15	–	0.3	< 0.001	< 0.001	< 0.001
	BD	0.17	0.17	0.45	0.14	0.002	–	< 0.001	< 0.001	0.009
	CD	− 0.01	0.28	0.13	0.06	0.22	0.23	–	0.002	0.1
South Sudan	South Sudan	0.29	0.69	− 0.003	0.41	0.52	0.59	0.19	–	< 0.001
Laboratory samples	LS	− 0.02	0.08	0.35	0.009	0.15	0.14	0.04	0.48	–

Notes: F_ST values below the diagonal and P-values above the diagonal; The genetic differentiation was considered as low (F_ST between 0–0.05), intermediate (F_ST between 0.05–0.15), great (F_ST between 0.15–0.25) and very great (F_ST < 0.25). The sample sizes (number of sequences) used in each population are shown in (Additional file 9: Table S7, Additional file 10: Table S8)
Abbreviations: AEZ, agro-ecological zones; BD, buffalo-derived; LS, laboratory samples; CD, cattle-derived

ISSN: 1756-3305