Fig. 1
From: A DAF-3 co-Smad molecule functions in Haemonchus contortus development
Amino acid sequence alignments for Hc-DAF-3 and homologues from Homo spaiens (Hs) and Mus musculus (Ms). a Alignments of the MH1 domain and the N-terminal sequence of the linker region. Abbreviations: NLS, nuclear localization signal; DBM, DNA-binding motif; NES, nuclear export signals. b Alignment of the C-terminal sequence of the linker region and the MH2 domain. Boxed sequence represent Smad4 activation domain (SAD). Marked in colour are NLS (red), DBM (blue) and NES (yellow). Consensus residues are marked in black; similar residues are marked in grey