Fig. 3

PGRP-LA is required for resistance to P. berghei. a Median oocyst number in dsRNA-treated mosquitoes. Each dot represents an individual mosquito and horizontal lines represent the medians. Results from one of three independent experiments are shown. Significance was determined by Mann–Whitney test (U = 132.00, P = 0.0003). b Relative expression levels of immune-related genes in dsRNA-treated mosquitoes 24 h post-infectious blood meal. Error bars indicate standard error of the mean (n = 8). Results from one of three independent experiments are shown. Significance was determined by Student’s t-test (for details, see Additional file 3: Text S1). *P < 0.05, **P < 0.01, ***P < 0.001. c Relative expression level of 16S in dsRNA-treated mosquitoes 24 h post-infectious blood meal. Each dot represents an individual mosquito and horizontal lines represent the medians. Significance was determined by Mann–Whitney test (U = 12.00, P = 0.0057)