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Table 1 In vivo efficacy of macrocyclic lactone products against Psoroptes ovis on 16 Belgian Blue beef farms in Belgium and the Netherlands

From: Resistance against macrocyclic lactones in Psoroptes ovis in cattle

Farm

No. of animals

Acaricide

RedMC (%)

95% CI

Resistance status

nTR

Mite-free proportion (%)

1

13

IVM

68.5

25.4–93.2

Resistant

> 7

0/13 (0)

2

10

IVM

99.3

97.7–100

Sensitive

4

8/10 (80)

3

9

IVM /DOR

33.3

− 65.8 to 87.6

Resistant

3

2/9 (22)

4

7

MOX-LA DOR

7.6

− 58.6 to 56.1

Resistant

> 4

0/7 (0)

5

9

IVM

− 36.8

− 200.7 to 63.0

Resistant

> 5

0/7 (0)

6

9

DOR

97.8

92.4–99.0

Sensitive

2

4/9 (44)

7

9

DOR

78.5

72.2–83.9

Resistant

4

2/9 (22)

8

9

IVM

-82.5

− 203.1 to 7.8

Resistant

5

2/9 (22)

9

10

DOR

97.8

94.0–99.7

Sensitive

3

5/10 (50)

10

9

MOX

89.7

65.4–99.5

Resistant

4

2/9 (22)

11

9

DOR

80.4

56.7–94.8

Resistant

2

3/9 (33)

12

9

DOR

95.8

86.2–99.8

Suspected resistant

4

1/9 (11)

13

8

DOR

50.3

29.7–67.8

Resistant

3

4/8 (50)

14

8

DOR

86.2

77.8–92.7

Resistant

3

5/8 (63)

15

10

DOR

65.5

51.6–77.0

Resistant

2

2/10 (20)

16

9

DOR

92.0

82.6–97.8

Resistant

3

3/9 (33)

  1. Abbreviations: CI, confidence interval; IVM, ivermectin injectable (Ivomec 1%®); DOR, doramectin injectable (Dectomax®); MOX, moxidectin injectable (Cydectin®); LA, moxidectin injectable long-acting formulation; RedMC, average reduction in mite counts on a given farm after the first treatment round; nTR, number of treatment rounds until all animals at a given farm had a mite count of zero; mite-free proportion, the proportion of the animals with negative mite counts after the first treatment round