Fig. 5From: Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and GiardiaAnalysis of cell death in promastigotes of L. infantum treated with alendronate. Negative control: promastigotes not treated with alendronate and stained with Annexin V and 7-AAD (a). Promastigotes treated with 10 µM miltefosine for 72 hours and stained with Annexin V and 7-AAD (b). Promastigotes treated with 100 µM alendronte for 72 hours and stained with Annexin V and 7-AAD (c). Promastigotes permeabilized with triton X-100, 0.5%, and stained with Annexin V and 7-AAD (d). SSC versus FSC (left panels); and FITC Annexin V (FL1) versus 7-AAD (FL3) (right panels)Back to article page