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Fig. 5 | Parasites & Vectors

Fig. 5

From: Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and Giardia

Fig. 5

Analysis of cell death in promastigotes of L. infantum treated with alendronate. Negative control: promastigotes not treated with alendronate and stained with Annexin V and 7-AAD (a). Promastigotes treated with 10 µM miltefosine for 72 hours and stained with Annexin V and 7-AAD (b). Promastigotes treated with 100 µM alendronte for 72 hours and stained with Annexin V and 7-AAD (c). Promastigotes permeabilized with triton X-100, 0.5%, and stained with Annexin V and 7-AAD (d). SSC versus FSC (left panels); and FITC Annexin V (FL1) versus 7-AAD (FL3) (right panels)

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