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Table 2 Mass spectrometry-based identification of membrane proteins obtained by IP

From: Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway

Protein ID

Gene

Uniprot identifier

Species

Protein MW

PI

UniquePepCount

SeqCoverage (%)

Annexin A2

ANXA2

sp|P07355|

Human

38603.6

7.57

8

20.94

Adenylyl cyclase-associated protein 1

CAP1

sp|Q01518|

Human

51900.86

8.24

7

13.47

Elongation factor 1-alpha 1

EEF1A1

sp|P68104|

Human

50140.28

9.1

8

14.94

Annexin A6

ANXA6

sp|P08133|

Human

75872.41

5.42

6

9.66

Heat shock protein HSP 90-beta

HSP90AB1

sp|P08238|

Human

83263.22

4.97

6

7.04

Hemoglobin subunit alpha

HBA1

sp|P69905|

Human

15257.36

8.72

6

26.76

Protein disulfide-isomerase

P4HB

sp|P07237|

Human

57115.66

4.76

4

6.10

Coiled-coil domain-containing protein 88B

CCDC88B

sp|A6NC98|

Human

164807.13

5.09

3

1.49

ATP-binding cassette sub-family F member 3

ABCF3

sp|Q9NUQ8|

Human

79743.72

5.95

3

3.53

ATP-binding cassette sub-family A member 13

ABCA13

sp|Q86UQ4|

Human

576152.47

6.01

3

0.42

Voltage-dependent anion-selective channel protein 1

VDAC1

sp|P21796|

Human

30772.21

8.62

3

13.43

Annexin A1

ANXA1

sp|P04083|

Human

38713.8

6.57

3

1.02

Annexin A5

ANXA5

sp|P08758|

Human

35936.34

4.94

3

8.75

Moesin

MSN

sp|P26038|

Human

67819.26

6.08

3

4.51

Ribosome-binding protein 1

RRBP1

sp|Q9P2E9|

Human

152470.38

8.69

3

0.99

Galectin-1

LGALS1

sp|P09382|

Human

26152

8.58

3

7.20

ADP/ATP translocase 1

SLC25A4

sp|P12235|

Human

33064.1

9.78

2

6.04

Myosin light polypeptide 6

MYL6

sp|P60660|

Human

16929.88

4.56

2

14.57

Neurobeachin

NBEA

sp|Q8NFP9|

Human

327817.78

5.78

2

0.48

PH-interacting protein

PHIP

sp|Q8WWQ0|

Human

206686.7

9.02

2

0.77

Golgi apparatus protein 1

GLG1

sp|Q92896|

Human

134550.64

6.57

2

1.02

Exocyst complex component 1

EXOC1

sp|Q9NV70|

Human

101980.39

6.17

2

0.67

E3 ubiquitin-protein ligase UBR4

UBR4

sp|Q5T4S7|

Human

573834.61

5.7

2

0.29

Protocadherin beta-4

PCDHB4

sp|Q9Y5E5|

Human

87269.06

5.05

2

1.51

Vacuolar protein sorting -associated protein 8 homolog

VPS8

sp|Q8N3P4|

Human

161751.77

5.41

2

0.77

Coronin-1A

CORO1A

sp|P31146|

Human

51025.7

6.25

2

5.86

ATP synthase subunit alpha, mitochondrial

ATP5A1

sp|P25705|

Human

59749.91

9.16

2

3.44

  1. Notes: The number of unique peptides detected by UniquePepCount: proteins are arranged from high to low according to the size of UniquePepCount, and the higher the value, the higher the reliability of the protein. SeqCoverage: peptide coverage, that is, the proportion of the number of amino acids detected to the full length of the protein (formula: the number of amino acids detected / the number of all amino acids of the protein). The higher the protein coverage, the higher the kurtosis of the protein may be relatively higher in this sample, but there is no absolute quantification standard
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ISSN: 1756-3305

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