Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway

Table 4 Statistical results of MAPK phospho-antibody microarray

Location	Protein description	Control group	Experimental group	(Con-Exp)/Con*% ratio	Regulation type
A1–A2	Reference spots	51937.73	51840.95	0.186338525	None
A21–A22	Reference spots	52784.42	51993.97	1.497506272	None
B3–B4	Akt1	3507.71	3485.56	0.631466113	None
B5–B6	Akt2	3006.91	2396.15	20.31188163	Down
B7–B8	Akt3	1071.16	1027.13	4.110497031	None
B9–B10	Akt pan	997.93	838.29	15.99711403	None
B11–B12	CREB	4019.41	2452.13	18.9927875	Down
B13–B14	ERK1	1344.72	828.83	38.36412041	Down
B15–B16	ERK2	631.38	167.43	73.4818968	Down
B17–B18	GSK-3alpha/beta	1387.87	1173.06	15.47767442	None
B19–B20	GSK-3beta	4955.93	6242.08	− 15.95173862	Up
C3–C4	HSP27	7084.96	16467.05	− 132.4226248	Up
C5–C6	JNK1	1410.1	1672.34	− 18.59726261	None
C7–C8	JNK2	2220.91	3306.2	− 48.86690591	Up
C9–C10	JNK3	1434.32	1113.73	− 22.35135813	None
C11–C12	JNK pan	1679.32	2675.34	− 59.31091156	Up
C13–C14	MKK3	1790.49	1580.41	11.73310099	None
C15–C16	MKK6	1871.84	1560.35	16.64084537	None
C17–C18	MSK2	2274.3	1893.44	16.74625159	None
D3–D4	p38alpha	2133.44	2407.17	− 12.83045223	None
D5–D6	p38beta	1383.76	1283.03	7.279441522	None
D7–D8	p38delta	2690.51	2296.87	14.6306834	None
D9–D10	p38gamma	1932.6	1822.39	5.702680327	None
D11–D12	p53	1426.09	1387.23	2.724933209	None
D13–D14	p70 S6 Kinase	1229.4	1264.16	− 2.827395477	None
D15–D16	RSK1	739.33	722.23	2.312904927	None
D17–D18	RSK2	1989.37	1881.12	5.441421153	None
D19–D20	TOR	2875.41	2469.84	14.10477115	None
E19–E20	NC	0	0		None
F1–F2	Reference spots	52455.55	49893.87	4.883525194	None

Notes: By default, the ratio ((Con-Exp)/Con*%)) of greater than ± 20% is considered significant
Abbreviations: down, downregulated; up, upregulated

ISSN: 1756-3305