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Table 3 Distribution of Borrelia persica and Borrelia burgdorferi sensu stricto spirochetes in tissues of immunodeficient NOD-SCID mice on day 49/50

From: Rapid clearance of Borrelia burgdorferi from the blood circulation

Inoculuma n Spirochetes in tissue samples detected by culture/qPCR (organisms/mg)
Ear Skin Joint Spleen Bladder Heart Brain
Intradermal
 B. persica (1.0 × 105)   #/0 #/17 #/199 +/873 +/74,518 +/14,017 +/3702
#/0 #/47,690 #/117 #/19 #/1743 #/46,102 #/10,721
#/0 #/11,529 +/262 −/3381 +/83,700 +/23,582 +/11,929
#/0 #/1171 #/574 +/1050 +/26,254 #/28,797 +/2639
#/0 #/311 #/24 #/144 #/131,872 #/6168 #/1896
 Positive mice 3/5 0/0 0/5 1/5 2/5 3/5 2/5 3/5
Intradermal
 B. burgdorferi sensu stricto (1.0 × 106)   #/48 #/41,467 +/20,395 +/22 +/266,594 +/360 +/11
#/522 #/18,795 +/37,393 +/537 +/217,600 #/333 +/12
#/3082 #/16,655 #/2113 #/14 +/2,110,835 +/357 +/15
#/10,372 #/18,435 +/40,571 #/3 +/1,141,583 +/1122 +/47
#/4,987 #/15,288 +/17,693 +/992 +/384,204 +/2057 +/12
 Positive mice 5/5 0/5 0/5 4/5 3/5 5/5 4/5 5/5
  1. aCulture-derived borreliae
  2. Key: #, contaminated culture; +, positive, with motile spirochetes in culture; −, negative, no spirochetes in culture