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Table 4 Distribution of Borrelia persica spirochetes in tissues of immunocompetent C3H/HeOuJ mice on day 49/50

From: Rapid clearance of Borrelia burgdorferi from the blood circulation

Inoculuma

n

Spirochetes in tissue samples by culture/qPCR (organisms/mg)

Ear

Skin

Joint

Spleen

Bladder

Heart

Brain

Intradermal

 B. persica (7.2 × 105)

 

#/0

#/0

−/0

−/0

−/0

−/0

+/39

#/0

#/0

−/0

−/0

−/0

−/0

+/31

#/0

−/0

−/0

−/0

−/0

−/0

+/89

#/0

#/0

−/0

−/0

−/0

−/0

+/59

#/0

−/0

−/0

−/0

−/0

−/0

+/136

 Positive mice

5/5

0/0

0/0

0/0

0/0

0/0

0/0

5/5

Intravenous

 B. persica (7.2 × 105)

 

#/0

#/0

−/0

−/0

−/0

−/0

+/30

#/0

#/0

−/0

−/0

−/0

−/0

+/34

−/0

−/0

−/0

−/0

−/0

−/0

+/75

#/0

#/0

−/0

−/0

−/0

−/0

+/216

#/0

#/0

−/0

−/0

−/0

−/0

+/63

#/0

#/0

−/0

−/0

−/0

−/0

+/74

 Positive mice

6/6

0/0

0/0

0/0

0/0

0/0

0/0

6/6

  1. aHost-adapted borreliae
  2. Key: #, contaminated culture; +, positive, with motile spirochetes in culture; −, negative, no spirochetes in culture