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Table 4 Distribution of Borrelia persica spirochetes in tissues of immunocompetent C3H/HeOuJ mice on day 49/50

From: Rapid clearance of Borrelia burgdorferi from the blood circulation

Inoculuma n Spirochetes in tissue samples by culture/qPCR (organisms/mg)
Ear Skin Joint Spleen Bladder Heart Brain
Intradermal
 B. persica (7.2 × 105)   #/0 #/0 −/0 −/0 −/0 −/0 +/39
#/0 #/0 −/0 −/0 −/0 −/0 +/31
#/0 −/0 −/0 −/0 −/0 −/0 +/89
#/0 #/0 −/0 −/0 −/0 −/0 +/59
#/0 −/0 −/0 −/0 −/0 −/0 +/136
 Positive mice 5/5 0/0 0/0 0/0 0/0 0/0 0/0 5/5
Intravenous
 B. persica (7.2 × 105)   #/0 #/0 −/0 −/0 −/0 −/0 +/30
#/0 #/0 −/0 −/0 −/0 −/0 +/34
−/0 −/0 −/0 −/0 −/0 −/0 +/75
#/0 #/0 −/0 −/0 −/0 −/0 +/216
#/0 #/0 −/0 −/0 −/0 −/0 +/63
#/0 #/0 −/0 −/0 −/0 −/0 +/74
 Positive mice 6/6 0/0 0/0 0/0 0/0 0/0 0/0 6/6
  1. aHost-adapted borreliae
  2. Key: #, contaminated culture; +, positive, with motile spirochetes in culture; −, negative, no spirochetes in culture