Table 5 Distribution of Borrelia burgdorferi sensu stricto spirochetes in tissues of immunocompetent C3H/HeOuJ mice on day 49/50
From: Rapid clearance of Borrelia burgdorferi from the blood circulation
Inoculuma | n | Spirochetes in tissue samples by culture/qPCR (organisms/mg) | ||||||
|---|---|---|---|---|---|---|---|---|
Ear | Skin | Joint | Spleen | Bladder | Heart | Brain | ||
Intradermal | ||||||||
 B. burgdorferi sensu stricto (3.5/2.8 × 103) |  | #/0 | +/0 | +/0 | #/0 | +/875 | +/0 | −/0 |
#/0 | +/0 | +/0 | +/0 | +/676 | +/0 | +/0 | ||
+/0 | +/0 | +/0 | +/0 | +/1041 | +/409 | −/0 | ||
#/0 | +/0 | +/0 | +/0 | +/1867 | +/0 | +/0 | ||
#/0 | #/0 | +/0 | +/0 | +/1482 | +/0 | −/0 | ||
+/0 | +/0 | +/0 | −/0 | +/2420 | +/893 | −/0 | ||
+/0 | +/0 | +/0 | −/0 | +/10,295 | +/501 | −/0 | ||
+/0 | +/0 | +/0 | −/0 | +/1383 | +/788 | −/0 | ||
#/0 | +/0 | +/0 | −/0 | +/2741 | +/817 | −/0 | ||
#/0 | +/0 | +/0 | −/0 | +/906 | +/109 | −/0 | ||
#/0 | +/0 | +/0 | −/0 | +/3487 | +/607 | −/0 | ||
 Positive mice | 11/11 | 4/0 | 10/0 | 11/0 | 4/0 | 11/11 | 11/7 | 2/0 |
Intravenous | ||||||||
 B. burgdorferi sensu stricto (3.5/2.8 × 103) |  | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | −/0 |
#/0 | −/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
#/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
#/0 | −/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
#/0 | −/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
−/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
−/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
−/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
#/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
#/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
#/0 | #/0 | −/0 | −/0 | −/0 | −/0 | −/0 | ||
 Positive mice | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 | 0/0 |