Skip to main content

Table 5 Distribution of Borrelia burgdorferi sensu stricto spirochetes in tissues of immunocompetent C3H/HeOuJ mice on day 49/50

From: Rapid clearance of Borrelia burgdorferi from the blood circulation

Inoculuma n Spirochetes in tissue samples by culture/qPCR (organisms/mg)
Ear Skin Joint Spleen Bladder Heart Brain
Intradermal
 B. burgdorferi sensu stricto (3.5/2.8 × 103)   #/0 +/0 +/0 #/0 +/875 +/0 −/0
#/0 +/0 +/0 +/0 +/676 +/0 +/0
+/0 +/0 +/0 +/0 +/1041 +/409 −/0
#/0 +/0 +/0 +/0 +/1867 +/0 +/0
#/0 #/0 +/0 +/0 +/1482 +/0 −/0
+/0 +/0 +/0 −/0 +/2420 +/893 −/0
+/0 +/0 +/0 −/0 +/10,295 +/501 −/0
+/0 +/0 +/0 −/0 +/1383 +/788 −/0
#/0 +/0 +/0 −/0 +/2741 +/817 −/0
#/0 +/0 +/0 −/0 +/906 +/109 −/0
#/0 +/0 +/0 −/0 +/3487 +/607 −/0
 Positive mice 11/11 4/0 10/0 11/0 4/0 11/11 11/7 2/0
Intravenous
 B. burgdorferi sensu stricto (3.5/2.8 × 103)   #/0 −/0 −/0 −/0 −/0 −/0 −/0
#/0 −/0 −/0 −/0 −/0 −/0 −/0
#/0 #/0 −/0 −/0 −/0 −/0 −/0
#/0 −/0 −/0 −/0 −/0 −/0 −/0
#/0 −/0 −/0 −/0 −/0 −/0 −/0
−/0 #/0 −/0 −/0 −/0 −/0 −/0
−/0 #/0 −/0 −/0 −/0 −/0 −/0
−/0 #/0 −/0 −/0 −/0 −/0 −/0
#/0 #/0 −/0 −/0 −/0 −/0 −/0
#/0 #/0 −/0 −/0 −/0 −/0 −/0
#/0 #/0 −/0 −/0 −/0 −/0 −/0
 Positive mice 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0
  1. aHost-adapted borreliae
  2. Key: #, contaminated culture; +, positive, with motile spirochetes in culture; −, negative, no spirochetes in culture