Table 2 Deltamethrin knockdown concentrations (KC₅₀ and KC₉₀) and resistance ratios (RR) for Aedes aegypti females in the parental generation (F_S0) and the deltamethrin-selected generations (F_S1–F_S5)

Merida

F_S0

345

1.85 (1.69–2.03)

3.89 (3.27–4.63)

2.95 (0.35)

< 0.001

20

8

F_S1

403

1.62 (1.45–1.82)

4.65 (3.62–5.97)

2.09 (0.21)

< 0.001

18

10

F_S2

525

1.85 (1.63–2.09)

6.75 (4.88–9.33)

1.69 (0.19)

< 0.001

20

14

F_S3

540

2.42 (2.04–2.85)

15.19 (14.58–21.80)

1.19 (0.10)

< 0.001

27

33

F_S4

440

2.55 (2.17–3.00)

12.79 (9.01–18.16)

1.36 (0.13)

< 0.001

28

27

F_S5

400

3.44 (2.93–4.04)

14.84 (10.88–20.23)

1.50 (0.15)

< 0.001

38

32

Progreso

F_S0

490

0.54 (0.45–0.64)

3.22 (2.26–4.60)

1.23 (0.11)

< 0.001

6

7

F_S1

526

0.67 (0.60–0.79)

3.00 (2.25–3.99)

1.50 (0.13)

< 0.001

7

7

F_S2

417

1.78 (1.53–2.07)

7.13 (4.84–10.50)

1.58 (0.18)

< 0.001

20

15

F_S3

395

1.57 (1.34–1.85)

7.04 (4.93–10.03)

1.47 (0.15)

< 0.001

17

15

F_S4

439

2.13 (1.88–2.40)

7.36 (5.47– 9.91)

1.77 (0.19)

< 0.001

23

16

F_S5

320

1.46 (1.27–1.68)

5.63 (4.57–6.93)

2.02 (0.22)

< 0.001

23

13

Hunucma

F_S0

355

0.34 (0.28–0.40)

1.42 (1.03–1.96)

1.16 (0.09)

< 0.001

3

3

F_S1

460

0.25 (0.21–0.29)

1.25 (0.88–1.76)

1.37 (0.12)

< 0.001

3

3

F_S2

597

0.33 (0.27–0.40)

3.27 (2.13–5.01)

0.96 (0.08)

< 0.001

4

7

F_S3

353

1.14 (0.90–1.45)

10.19 (5.53–18.80)

1.00 (0.12)

< 0.001

13

22

F_S4

220

1.16 (1.06–1.26)

1.93 (1.69–2.20)

4.30 (0.62)

< 0.001

13

4

F_S5

180

0.75 (0.61–0.91)

2.26 (1.62–3.16)

1.98 (0.33)

< 0.001

8

5

Hoctun

F_S0

535

0.48 (0.41–0.56)

1.85 (1.48–2.32)

1.63 (0.14)

< 0.001

5

4

F_S1

535

0.23 (0.19–0.27)

1.32 (0.97–1.80)

1.35 (0.10)

< 0.001

2

3

F_S2

470

0.48 (0.38–0.61)

5.73 (3.47–9.46)

0.88 (0.08)

< 0.001

5

12

F_S3

508

0.57 (0.48–0.67)

2.92 (2.13–3.99)

1.34 (0.12)

< 0.001

6

6

F_S4

380

0.75 (0.65–0.86)

2.61 (1.92–3.56)

1.76 (0.23)

< 0.001

8

6

F_S5

440

0.94 (0.79–1.12)

4.19 (3.09–5.66)

1.47 (0.14)

< 0.001

10

9

Agua Dulce

F_S0

536

0.80 (0.76–0.84)

1.44 (1.30–1.60)

3.73 (0.30)

< 0.001

9

3

F_S1

480

1.06 (1.01–1.12)

1.80 (1.62–2.01)

4.15 (0.38)

< 0.001

12

4

F_S2

333

1.08 (1.00–1.16)

1.99 (1.70–2.33)

3.58 (0.45)

< 0.001

12

4

F_S3

313

1.06 (0.97–1.15)

2.06 (1.74–2.44)

3.32 (0.38)

< 0.001

12

4

F_S4

397

1.14 (1.05–2.03)

2.42 (2.03–2.89)

2.92 (0.32)

< 0.001

13

5

F_S5

440

1.09 (1.02–1.17)

2.04 (1.79–2.33)

3.53 (0.34)

< 0.001

12

5

Jose Cardel

F_S0

420

1.26 (1.21–1.34)

2.18 (1.95–2.48)

4.01 (1.18)

< 0.001

14

5

F_S1

429

1.47 (1.33–1.64)

4.10 (3.28–5.12)

2.15 (0.20)

< 0.001

16

9

F_S2

499

1.63 (1.51–1.75)

3.73 (3.08–4.50)

2.65 (0.28)

< 0.001

18

8

F_S3

400

1.68 (1.53–1.85)

4.07 (3.35–4.95)

2.48 (0.24)

< 0.001

19

9

F_S4

400

1.98 (1.74–2.24)

6.68 (5.03–8.86)

1.80 (0.19)

< 0.001

22

14

F_S5

360

2.01 (1.79–2.26)

5.68 (4.35–7.42)

2.12 (0.23)

< 0.001

22

12

New Orleans (NO)^e

–

492

0.09 (0.08–0.11)

0.46 (0.32-0.65)

1.43 (0.13)

< 0.001

–

–