Table 3 Deltamethrin knockdown concentrations (LC₅₀ and LC₉₀) and resistance ratios (RR) for Aedes aegypti females in the parental generation (F_S0) and the deltamethrin-selected generations (F_S1–F_S5)

Merida

F_S0

466

5.35 (4.73–6.56)

42.11 (27.77–63.84)

1.06 (0.09)

< 0.001

134

140

F_S1

584

5.60 (5.02–6.24)

18.63 (15.07–23.03)

1.82 (0.15)

< 0.001

140

62

F_S2

525

5.80 (5.16–6.49)

19.32 (19.96–30.27)

1.82 (0.18)

< 0.001

145

64

F_S3

520

7.87 (7.03–8.82)

24.58 (19.96–30.27)

1.93 (0.17)

< 0.001

196

82

F_S4

501

7.73 (6.93–8.61)

24.15 (19.69–29.62)

1.92 (0.17)

< 0.001

193

80

F_S5

389

7.88 (6.91–9.00)

26.31 (19.84–34.89)

1.82 (0.21)

< 0.001

197

88

Progreso

F_S0

650

0.75 (0.59–1.06)

7.06 (4.83–10.31)

0.97 (0.08)

< 0.001

18

23

F_S1

473

1.06 (0.86–1.29)

7.72 (5.21–11.44)

1.10 (0.09)

< 0.001

26

26

F_S2

415

1.71 (1.45–2.01)

7.19 (5.30–9.76)

1.53 (0.15)

< 0.001

43

24

F_S3

458

2.37 (2.08–2.71)

8.97 (6.74–11.95)

1.65 (0.15)

< 0.001

59

30

F_S4

461

2.06 (1.86–2.28)

5.63 (4.57–6.93)

2.18 (0.20)

< 0.001

51

19

F_S5

320

1.66 (1.46–1.88)

4.32 (3.23–5.78)

2.02 (0.22)

< 0.001

36

14

Hunucma

F_S0

424

0.25 (0.20–0.29)

1.43 (0.99–2.05)

1.24 (0.12)

< 0.001

6

5

F_S1

359

0.69 (0.53–0.78)

3.50 (2.32–5.28)

1.30 (0.14)

< 0.001

17

12

F_S2

497

0.80 (0.69–0.93)

3.63 (2.68–4.91)

1.45 (0.14)

< 0.001

20

12

F_S3

299

1.16 (1.01–1.33)

3.61 (2.69–4.83)

1.93 (0.23)

< 0.001

29

12

F_S4

260

1.33 (1.16–1.52)

3.26 (2.62–4.04)

2.45 (0.26)

< 0.001

33

11

F_S5

318

1.36 (1.19–1.56)

4.29 (3.20–5.75)

1.92 (0.22)

< 0.001

34

14

Hoctun

F_S0

532

1.30 (1.15–1.46)

4.06 (3.25–5.08)

1.92 (0.16)

< 0.001

32

13

F_S1

416

2.50 (2.23–2.79)

6.67 (5.51–8.07)

2.23 (0.22)

< 0.001

62

22

F_S2

467

3.27 (3.01–3.55)

7.43 (6.28–8.78)

2.67 (0.27)

< 0.001

82

23

F_S3

417

2.76 (2.52–3.02)

6.60 (5.45–8.00)

2.52 (0.26)

< 0.001

69

22

F_S4

457

2.67 (2.45–2.92)

6.51 (5.36–7.89)

2.47 (0.26)

< 0.001

67

22

F_S5

359

2.07 (1.89–2.27)

4.37 (3.72–5.13)

2.94 (0.33)

< 0.001

52

15

Agua Dulce

F_S0

475

1.00 (0.91–1.09)

2.62 (2.14–3.21)

2.27 (0.21)

< 0.001

25

7

F_S1

540

1.41 (1.31–1.52)

3.15 (2.65–3.75)

2.74 (0.24)

< 0.001

32

10

F_S2

420

2.02 (1.81–2.25)

5.51 (4.49–6.78)

2.18 (0.21)

< 0.001

50

18

F_S3

457

2.12 (1.90–2.35)

6.19 (4.91–7.73)

2.05 (0.19)

< 0.001

53

20

F_S4

519

2.03 (1.86–2.22)

5.32 (4.40–6.44)

2.28 (0.20)

< 0.001

51

18

F_S5

340

1.95 (1.74–2.20)

6.40 (4.79–8.55)

1.85 (0.19)

< 0.001

49

21

Jose Cardel

F_S0

481

1.64 (1.46–1.83)

5.22 (4.10–6.64)

1.89 (0.18)

< 0.001

41

6

F_S1

531

2.30 (2.12–2.49)

5.33 (4.53–6.28)

2.61 (0.25)

< 0.001

57

18

F_S2

460

2.43 (2.21–2.67)

6.01 (4.95–7.30)

2.42 (0.22)

< 0.001

60

20

F_S3

360

2.35 (2.14–2.58)

5.12 (4.33–6.06)

2.82 (0.27)

< 0.001

56

17

F_S4

420

2.26 (2.07–2.45)

4.93 (4.27–5.69)

2.81 (0.25)

< 0.001

56

16

F_S5

320

2.84 (2.63–3.08)

5.49 (4.67–6.44)

3.34 (0.34)

< 0.001

71

18

New Orleans (NO)^e

–

492

0.04 (0.03–0.05)

0.30 (0.21–0.45)

1.11 (0.10)

< 0.001

–

–