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Fig. 2 | Parasites & Vectors

Fig. 2

From: Two old drugs, NVP-AEW541 and GSK-J4, repurposed against the Toxoplasma gondii RH strain

Fig. 2

NVP-AEW541 and GSK-J4 HCl display dose-dependent inhibitory effects on T. gondii growth. a Structures and molecular weights of NVP-AEW541 and GSK-J4 HCl. b Dose-response response curves and IC50 values for NVP-AEW541 and GSK-J4 HCl. RH-2F parasite-infected HFFs were incubated with serial dilutions (0 to 100 μM) of the test compounds, and β-Gal activity was measured. c Dose-response response curves and TD50 values for NVP-AEW541 and GSK-J4 HCl. HFFs were incubated with serial dilutions (0 to 100 μM) of the test compounds, and cell growth was measured by using CCK8

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