Fig. 2From: Recent advances on innate immune pathways related to host–parasite cross-talk in cystic and alveolar echinococcosisBcl-2-specific siRNA/mRNA pathway schematization. dsRNA molecules are cleaved by the nuclease Dicer (1) and converted to siRNA (2). Bcl-2-specific siRNA incorporated into a multiprotein RNA-inducing silencing complex (RISC) (3). The RISC attached to complementary target mRNA (4) and subsequent endonucleolytic cleavage and gene silencing (5)Back to article page