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Fig. 6 | Parasites & Vectors

Fig. 6

From: Xiaochaihu decorction relieves liver fibrosis caused by Schistosoma japonicum infection via the HSP47/TGF-β pathway

Fig. 6

Xiaochaihu (XCH) decoction inhibited Schistosoma japonicum induced fibrogenic cytokine production by fibroblasts. NIH3T3 cells were treated with S. japonicum egg antigens in the presence or absence of Xiaochaihu decoction, LY2157299 and shRNA-HSP47. The medium levels of TGF-β (a), IL-13 (b), and IL-17 (c) of NIH3T3 cells were measured by ELISA. Abbreviations: SJ-A, S. japonicum egg antigens. **P < 0.01 compared to control, #P < 0.05 compared to infection, ##P < 0.01 compared to infection

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