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Fig. 8 | Parasites & Vectors

Fig. 8

From: Xiaochaihu decorction relieves liver fibrosis caused by Schistosoma japonicum infection via the HSP47/TGF-β pathway

Fig. 8

A proposed model for explaining how XCH alleviates S. japonicum infection induced liver fibrosis. XCH inhibits S. japonicum infection, survival, and proliferation in mouse liver, depresses S. japonicum infection induced upregulation of HSP47 and TGF-β production, and inhibits S. japonicum-caused inflammation, which in turn blocks the activation of hepatic stellate cells and ECM deposition

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Parasites & Vectors

ISSN: 1756-3305

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