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Table 4 Poisson regression model with pooled arms

From: Individuals living in an onchocerciasis focus and treated three-monthly with ivermectin develop fewer new onchocercal nodules than individuals treated annually

Variable

Saturated model

Stepwise model

b (95% CI)

P-value

b (95% CI)

P-value

Increase in no. of new nodules for each additional initial nodulea

 Annual treatment

0.055 (0.030–0.080)

< 0.001

0.058 (0.035–0.081)

< 0.001

 3-monthly treatment

0.023 (0.0004–0.046)

0.045

0.026 (0.005–0.048)

0.014

 Age

0.005 (0.0001–0.010)

0.045

0.006 (0.002–0.009)

0.002

 Weight

− 0.007 (− 0.005–0.003)

0.703

  

CMFL in the village of residence

 Low

Ref.

   

 Middle

0.089 (− 0.153–0.332)

0.470

  

 High

0.149 (− 0.074–0.372)

0.191

  

MFD

 0–30 mf/mg

Ref.

 

Ref.

 

 31–80 mf/mg

0.084 (− 0.108–0.277)

0.389

0.102 (− 0.081–0.285)

0.275

 81–170 mf/mg

0.265 (0.082–0.447)

0.004

0.290 (0.117–0.463)

0.001

 > 171 mf/mg

0.358 (0.181–0.535)

< 0.001

0.383 (0.217–0.550)

< 0.001

P of the model

< 0.001

< 0.001

 

AIC

1648

1644

 

BIC

1686

1669

 

Log likelihood

− 815.2

− 816.3

 
  1. aThe reference is defined as annual treatment and 2 initial nodules
  2. Abbreviations: b, regression coefficient; 95% CI, 95% confidence interval; Ref., reference; CMFL, community microfilarial load; MFD, microfilarial density; AIC, Akaike’s information criterion; BIC, Bayesian information criterion