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Table 4 Poisson regression model with pooled arms

From: Individuals living in an onchocerciasis focus and treated three-monthly with ivermectin develop fewer new onchocercal nodules than individuals treated annually

VariableSaturated modelStepwise model
b (95% CI)P-valueb (95% CI)P-value
Increase in no. of new nodules for each additional initial nodulea
 Annual treatment0.055 (0.030–0.080)< 0.0010.058 (0.035–0.081)< 0.001
 3-monthly treatment0.023 (0.0004–0.046)0.0450.026 (0.005–0.048)0.014
 Age0.005 (0.0001–0.010)0.0450.006 (0.002–0.009)0.002
 Weight− 0.007 (− 0.005–0.003)0.703  
CMFL in the village of residence
 LowRef.   
 Middle0.089 (− 0.153–0.332)0.470  
 High0.149 (− 0.074–0.372)0.191  
MFD
 0–30 mf/mgRef. Ref. 
 31–80 mf/mg0.084 (− 0.108–0.277)0.3890.102 (− 0.081–0.285)0.275
 81–170 mf/mg0.265 (0.082–0.447)0.0040.290 (0.117–0.463)0.001
 > 171 mf/mg0.358 (0.181–0.535)< 0.0010.383 (0.217–0.550)< 0.001
P of the model< 0.001< 0.001 
AIC16481644 
BIC16861669 
Log likelihood− 815.2− 816.3 
  1. aThe reference is defined as annual treatment and 2 initial nodules
  2. Abbreviations: b, regression coefficient; 95% CI, 95% confidence interval; Ref., reference; CMFL, community microfilarial load; MFD, microfilarial density; AIC, Akaike’s information criterion; BIC, Bayesian information criterion