Table 5 Poisson regression model (with interaction term between initial number of nodules and treatment arms)

Increase in no. of new nodules for each additional initial nodule^a

 150 µg/kg annually

0.043 (0.014–0.071)

0.004

0.046 (0.019–0.073)

0.001

 800 µg/kg annually

0.067 (0.039–0.095)

< 0.001

0.070 (0.043–0.096)

< 0.001

 150 µg/kg 3-monthly

0.021 (− 0.004–0.047)

0.106

0.024 (− 0.000–0.048)

0.052

 800 µg/kg 3-monthly

0.026 (− 0.001–0.053)

0.063

0.029 (0.004–0.056)

0.026

Age

0.005 (− 0.00001–0.010)

0.051

0.006 (0.002–0.009)

0.003

Weight

− 0.001 (− 0.005–0.003)

0.659

CMFL in the village of residence

 Low

Ref.

 Middle

0.090 (− 0.154–0.333)

0.470

 High

0.151 (− 0.072–0.375)

0.185

MFD

 0–30 mf/mg

Ref.

Ref.

 31–80 mf/mg

0.089 (− 0.103–0.281)

0.364

0.105 (− 0.079–0.288)

0.263

 81–170 mf/mg

0.278 (0.095–0.461)

0.003

0.301 (0.128–0.474)

0.001

 > 171 mf/mg

0.371 (0.194–0.549)

< 0.001

0.394 (0.227–0.561)

< 0.001

P of the likelihood-ratio test for the interaction term: 0.035

 P of the model

< 0.001

< 0.001

 AIC

1649

1645

 BIC

1695

1678

 Log likelihood

− 813.5

− 814.6