Fig. 2
PfArp4 is involved in the centromere biology. a Average number of merozoites per schizont in PfArp4-Ty1-Ribo lines cultured with versus without GlcN. (Mann-Whitney U-test: U(50) = 106.5, Z = − 7.93, P < 0.0001). Upper: representative Giemsa-stained parasite at late schizont stage. b Average number of merozoites per schizont in Pf3D7-G7 lines cultured with versus without GlcN. (Mann-Whitney U-test: U(50) = 1120, Z = − 0.906, P = 0.365). Upper: representative Giemsa-stained parasite at late schizont stage. c Average profile of PfArp4 enrichment at ring stage (log2[PfArp4 ChIP-normalized read coverage/input-normalized read coverage])relative to centromere for all chromosomes. d Average profile of H2A.Z enrichment at ring stage (log2[H2A.Z ChIP-normalized read coverage/input-normalized read coverage])relative to centromere for all genes with (PfArp4 KD H2A.Z/input) or without (PfArp4 H2A.Z/input) GlcN for PfArp4 knockdown. e Track view showing the signals atindividual centromeres of PfArp4 (log2[PfArp4/input]) and H2A.Z with (log2[PfArp4 KD H2A.Z/input]) or without (log2[PfArp4 H2A.Z/input]) GlcN for PfArp4 knockdown