Table 1 Parameters used for the individual-based, stochastic simulation models

Transmission rate, R₀

2.12

2.2

Aggregation of worms within human hosts, k

0.15

0.35 [25]

Relative exposure to infection and contribution to infective reservoir (assuming no differences between males and females)

0–2 years-old: 0.22

0–2 years-old: 0.03

2–5 years-old: 1.88

2–5 years-old: 0.09

5–15 years-old: 1

5–15 years-old: 1

15+ years-old: 0.53

15+ years-old: 2.5 [49]

Average worm life expectancy (years) (assuming an exponential distribution)

1 [50]

2 [51]

Female worm fecundity, γ

0.07 [37]

0.02 (assuming exponential saturation) [52]

Infectious reservoir decay rate (mean)

2 months [35]

12 days [51]

Drug efficacy

0.99 [40]

0.948 [40]