Treatment | Oral dosage | Days of treatment | No. of infected dogsa | Adult D. immitis worm counts | Efficacy compared to negative controlc | |
---|---|---|---|---|---|---|
Individual worm counts | Geometric meanb | % Reduction | ||||
Negative Control | NA | 0, 30, 60, 90, 120, 150 | 6 of 6 | 30, 33, 33, 33, 35, 37 | 32.9f | na |
Moxidectin | 24 µg/kg | 0, 30, 60, 90 | 5 of 6 | 0, 1, 1, 2, 2, 4 | 1.3g | 95.9 |
Moxidectin | 24 µg/kg | 0, 30, 60, 90, 120, 150 | 2 of 6 | 0, 0, 0, 0, 1, 1 | 0.2h | 99.3 |
Heartgard® Plus | min of 6 µg/kgd | 0, 30, 60, 90, 120, 150 | 6 of 6 | 6, 9, 13, 14, 17, 18 | 11.9i | 63.9 |
Interceptor® Plus | min. of 500 µg/kge | 0, 30, 60, 90, 120, 150 | 6 of 6 | 10, 13, 14, 16, 19, 22 | 14.9i | 54.6 |