Evaluation of oral fluralaner (Bravecto®) for efficacy against nymphs of Amblyomma americanum and Rhipicephalus sanguineus (sensu lato)

Table 2 Percent efficacy of fluralaner based on all live and live-fed Rhipicephalus sanguineus (sensu lato) nymphs from control and treated dogs (Experiment 1). Each group had 10 dogs

Infestation day	Count day	Control		Fluralaner						Efficacy
Infestation day	Count day	GM (L)	GM (LF)	GM (L)	GM (LF)	t-value (L)	t-value (LF)	P-value (L)	P-value (LF)	% (L)	% (LF)
− 1	1	37.3	25.6	0.9	0.1	t_(18.0) = 12.8	t_(18.0) = 26.8	< 0.001	< 0.001	97.7	99.7
− 1	2	30.1	29.8	0.1	0.0	t_(9.0) = 28.0	t_(18.0) = 30.5	< 0.001	< 0.001	99.8	100
6	8	28.1	25.7	1.0	0.0	t_(18.0) = 9.0	t_(18.0) = 29.9	< 0.001	< 0.001	96.4	100
6	9	29.7	29.7	0.0	0.0	t_(9.0) = 41.0	t_(18.0) = 41.0	< 0.001	< 0.001	100	100
28	30	15.5	12.6	2.5	0.0	t_(9.0) = 5.8	t_(18.0) = 14.7	< 0.001	< 0.001	83.7	100
28	31	21.4	20.4	0.1	0.0	t_(9.0) = 20.4	t_(18.0) = 21.9	< 0.001	< 0.001	99.3	100
56	58	13.6	10.0	2.3	0.0	t_(9.0) = 6.6	t_(18.0) = 13.6	< 0.001	< 0.001	82.9	100
56	59	21.7	21.6	0.2	0.0	t_(9.0) = 18.1	t_(18.0) = 23.8	< 0.001	< 0.001	99.1	100
84	86	19.9	16.3	2.6	0.7	t_(9.0) = 6.2	t_(9.0) = 7.0	< 0.001	< 0.001	86.7	95.7
84	87	24.7	23.8	0.9	0.6	t_(9.0) = 7.5	t_(9.0) = 7.5	< 0.001	< 0.001	96.3	97.5

Abbreviations: GM, geometric mean; L, all live (attached and engorged, attached and not engorged, free and engorged, and free and not engorged); LF, live-fed (attached and engorged, attached and not engorged, and free and engorged)

ISSN: 1756-3305