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Table 3 Percent efficacy of fluralaner based on all live and live-fed Amblyomma americanum nymphs from control and treated dogs (Experiment 2). Each group had 10 dogs

From: Evaluation of oral fluralaner (Bravecto®) for efficacy against nymphs of Amblyomma americanum and Rhipicephalus sanguineus (sensu lato)

Infestation day

Count day

Control

Fluralaner

Efficacy

GM (L)

GM (LF)

GM (L)

GM (LF)

t-value (L)

t-value (LF)

P-value (L)

P-value (LF)

% (L)

% (LF)

− 1

1

41.3

41.3

2.1

1.6

t(18.0) = 9.8

t(18.0) = 10.3

< 0.001

< 0.001

94.9

96.2

2

40.8

40.8

1.2

1.2

t(9.0) = 11.2

t(9.0) = 11.2

< 0.001

< 0.001

97.1

97.1

6

8

40.5

40.2

0.8

0.5

t(18.0) = 14.7

t(18.0) = 17.6

< 0.001

< 0.001

98.1

98.7

9

45.7

45.7

0.6

0.6

t(9.0) = 16.0

t(9.0) = 16.0

< 0.001

< 0.001

98.7

98.7

28

30

43.0

42.0

0.8

0.6

t(18.0) = 14.2

t(18.0) = 16.5

< 0.001

< 0.001

98.1

98.6

31

42.5

42.4

0.4

0.3

t(9.0) = 14.9

t(18.0) = 16.1

< 0.001

< 0.001

99.0

99.2

56

58

41.4

41.0

5.1

3.4

t(9.0) = 5.7

t(9.0) = 5.5

< 0.001

< 0.001

87.8

91.6

59

37.2

36.9

2.4

2.3

t(18.0) = 5.6

t(18.0) = 5.7

< 0.001

< 0.001

93.5

93.9

84

86

37.2

37.0

11.8

10.9

t(18.0) = 2.6

t(18.0) = 2.6

0.019

0.019

68.3

70.6

87

35.6

35.5

7.8

7.8

t(9.0) = 2.9

t(9.0) = 2.9

0.018

0.019

78.0

78.0

  1. Abbreviations: GM, geometric mean; L, all live (attached and engorged, attached and not engorged, free and engorged, and free and not engorged); LF, live-fed (attached and engorged, attached and not engorged, and free and engorged)