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Fig. 4 | Parasites & Vectors

Fig. 4

From: Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes

Fig. 4

Excretory/secretory products of Angiostrongylus cantonensis L5 stimulate the activation of ER stress-related pathways in astrocytes. Cells were treated with 0, 31.3, 62.5, 125 or 250 μg/ml excretory/secretory products (ESPs) of A. cantonensis L5 for 12 h. The mRNA (a) and protein (b) expression levels of ER stress-related molecules were detected by real-time qPCR and western blotting. The data are expressed as the mean ± SD from three independent experiments (n = 3). *P < 0.05 and **P < 0.01 compared cells treated with 0 μg/ml ESPs of A. cantonensis L5 for 12 h

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Parasites & Vectors

ISSN: 1756-3305

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