Fig. 3
From: IL-33/ST2 axis is involved in disease progression in the spleen during Leishmania donovani infection
Quantification of L. donovani parasite loads in the spleen. Mice were sacrificed at the indicated time points after infection and parasites were quantified by quantitative PCR targeting Leishmania 18S RNA and expressed by mg of tissue. Data show means ± SE of parasite loads from representative experiments performed on groups of 3 to 6 mice, comparing BALB/c wt and ST2-KO (a), B6 wt and IL-33-KO (b), BALB/c wt and B6 wt (c), BALB/c treated or not with rIL-33 (d) and B6 treated or not with rIL-33 (e). *P < 0.05, **P < 0.01, ***P < 0.001; Mann-Whitney test)