Fig. 5
From: IL-33/ST2 axis is involved in disease progression in the spleen during Leishmania donovani infection
Quantification of mRNA induction of cytokines, chemokines and immune effectors in the spleen of L. donovani-infected B6 mice. mRNA induction was quantified by quantitative PCR in liver extracts at various time points after infection and normalized by comparison to 18S mRNA. Expression of IFN-γ (a), TNF-α (b), IL-1β (c), in wt and IL-33 KO B6 mice. Expression of IFN-γ (d), TNF- α (e), IL-1β (f), iNOS (g), IL-12 (h) and TGF-β (i) in B6 mice treated with rIL-33 or untreated (wt) (2-way ANOVA comparison: *P < 0.05, **P < 0.01, ***P < 0.001)