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Table 2 Number of positive samples by qPCR (n), mean DNA copy number per µl and 95% confidence intervals, stratified by soil-transmitted helminth intensity of infection grouping

From: The increased sensitivity of qPCR in comparison to Kato-Katz is required for the accurate assessment of the prevalence of soil-transmitted helminth infection in settings that have received multiple rounds of mass drug administration

Species

Intensity group by Kato-Katz

Negative

Low

Medium

High

n

Mean DNA copy number/µl (95% CI)

n

Mean DNA copy number/µl (95% CI)

n

Mean DNA copy number/µl (95% CI)

n

Mean DNA copy number/µl (95% CI)

Ascaris lumbricoides

623

203.77 (83.09–423.08)

11

70598.89 (42892.01–97456.66)

11

539384.33 (303364.28–994523.32)

3

1202662.65 (256585.80–2048046.53)

Trichuris trichiura

566

170.28 (112.25–305.51)

74

2159.36 (1548.19–3344.78)

8

20110.37 (11082.89–35039.10)

0

.

Hookworms

606

 

42

 

0

 

0

 

Necator americanus

 

326466.03 (55039.74–1112959.65)

 

7232805.61 (4158351.54–13601987.63)

 

.

 

.

Ancylostoma duodenale

 

.

.

.

Ancylostoma ceylanicum

18547.90 (5566.54–53187.54)

1097750.25 (292621.84–2836328.32)

.

.

  1. Note: Intensity group cut-offs as defined by the WHO [37]