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Table 5 Adjusted effects of mosquito-disseminated pyriproxyfen on Aedes egg-trap-derived endpoints: numerical results of the top-ranking (smallest-BIC) zero-inflated generalized linear mixed model

From: Measuring mosquito control: adult-mosquito catches vs egg-trap data as endpoints of a cluster-randomized controlled trial of mosquito-disseminated pyriproxyfen

Term Estimate SE 95% CI
Lower Upper
Egg-count submodel
Fixed effects
Intercept (CC, BP)a 3.957 0.203 3.558 4.355
Intervention period (IP) − 0.296 0.225 − 0.736 0.145
Intervention cluster (IC) − 0.055 0.229 − 0.504 0.394
IP × IC 0.262 0.244 − 0.215 0.740
Temperatureb 0.695 0.113 0.473 0.917
Random effects SD
Dwelling ID 0.270 - 0.152 0.478
Month 0.244 - 0.115 0.519
Egg-trap negativity submodel
Fixed effects
Intercept (CC, BP)c 1.204 0.404 0.412 1.996
Intervention period (IP) 0.440 0.436 − 0.414 1.293
Intervention cluster (IC) 0.797 0.312 0.186 1.407
IP × IC − 0.251 0.311 − 0.861 0.360
Temperatureb − 1.255 0.200 − 1.646 − 0.863
Random effects SD
Dwelling ID 0.576 0.403 0.823
Month 0.593 0.384 0.916
  1. aThe intercept of the negative binomial (egg count) submodel estimates the (log-scale) expected mean number of Aedes eggs per egg-trap in CC, in the typical dwelling and at typical temperatures, during the BP; the other fixed-effect slope coefficients estimate changes in this expectation associated with period, cluster, intervention, and temperature effects; only this latter was clearly (sensu [55]) different from zero
  2. bSpecified as the (standardized) mean of minimum daily temperatures in the week before each sampling occasion (‘tmin_w’); the original variable had mean = 17.86 °C and SD = 2.89 °C. Given our focus on estimating adjusted intervention effects, we considered weather covariates as confounders; ‘tmin_w’ yielded better-performing models, as measured by BIC scores, than other measures of temperature and rainfall
  3. cThe intercept of the binomial (egg-trap negativity) submodel estimates the (logit-scale) expected proportion of negative egg-traps in the CC, in the typical dwelling and at typical temperatures, during the BP; the other fixed-effect slope coefficients estimate changes in this expectation associated with period, cluster, intervention, and temperature effects – with results suggesting higher baseline odds of egg-trap negativity in the CC and that warmer nights were independently associated with lower odds of egg-trap negativity
  4. Abbreviations: BIC, Bayesian information criterion; SE, standard error; 95% CI, 95% confidence interval (lower/upper limits); CC, control cluster; BP, baseline period; IP, intervention period; IC, intervention cluster; SD, standard deviation; ID, identity of each sampling dwelling