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Fig. 1 | Parasites & Vectors

Fig. 1

From: Physiological evidence that three known mutations in the para-sodium channel gene confer cypermethrin knockdown resistance in Rhipicephalus microplus

Fig. 1

Differential sensitivity of the acaricide susceptible (Su) strain and the multiple acaricide-resistant strain (San Alfonso). Tick ovary contraction was measured using videometrical analysis. Three µM of cypermethrin is sufficient to block most of the ovary contraction induced by nerve depolarization with 15 mM KCl. Higher concentrations of 5 and 9 µM totally block ovary contraction on the susceptible strain (cyper). Ovaries from the resistant strain (cyperresist) still respond and contract at higher concentrations (5 and 15 µM). All traces (time series) represent the normalized averaged response of nine preparations for each condition. Error bars show the standard error for each video frame. All experimental conditions tested were compared to the DMSO control and all of them were significantly different from it (P ≤ 0.001). Abbreviations: cyper, susceptible; cyperresist, resistant; DMSO, control

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