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Table 2 Overview of results obtained during the determination of the optimal threshold for MALDI-TOF MS identification

From: MALDI-TOF MS: optimization for future uses in entomological surveillance and identification of mosquitoes from New Caledonia

Species in the database Optimal threshold TP FN TN FP Sensitivity Specificity PPV NPV AUC 95% CI (AUC)
An. bancroftii 1.48 7 0 217 0 1 1 1 1 1 1–1
Ae. scutellaris 1.75 9 1 214 0 0.9 1 0.9 1 0.90 0.77–1
Ae. aegypti 1.77 18 1 205 0 0.97 1 0.95 1 0.97 0.92–1
Ae. notoscriptus 1.75 19 0 205 0 1 1 1 1 1 1–1
Ae. vigilax 1.57 17 3 204 0 0.85 1 0.85 1 0.85 0.75–0.96
Ae. vexans 1.57 16 4 204 0 0.8 1 0.80 1 0.85 0.75–0.96
Cx. quinquefasciatus 1.79 29 1 190 4 0.97 0.98 0.97 0.98 0.97 0.92–1
Cx. iyengari 1.77 18 0 205 1 1 0.99 1 0.99 0.99 0.99–1
Cx. sitiens 1.64 20 0 214 0 1 1 1 1 1 1–1
Cx. annulirostris 1.78 29 1 190 4 0.97 0.98 0.97 0.98 0.99 0.97–1
T. melanesiensis 1.7 20 0 204 0 1 1 1 1 1 1–1
Six speciesa 1.70 109 8 100 7 0.93 0.93 0.93 0.93 0.94 0.91–0.97
Five speciesb 1.63 101 6 110 7 0.94 0.95 0.94 0.94 0.96 0.94–0.99
  1. aAn. bancroftii, Ae. scutellaris, Ae. aegypti, Ae. vigilax, Cx. quinquefasciatus, Cx. sitiens
  2. bAe. notoscriptus, Ae. vexans, Cx. iyengari, Cx. annulirostris, T. melanesiensis
  3. Abbreviations: AUC, area under the curve; TP, true positives; FN, false negatives; TN, true negatives; FP, false positives; PPV, positive predictive values; NPV, negative predictive values