Table 2 Overview of results obtained during the determination of the optimal threshold for MALDI-TOF MS identification
Species in the database | Optimal threshold | TP | FN | TN | FP | Sensitivity | Specificity | PPV | NPV | AUC | 95% CI (AUC) |
|---|---|---|---|---|---|---|---|---|---|---|---|
An. bancroftii | 1.48 | 7 | 0 | 217 | 0 | 1 | 1 | 1 | 1 | 1 | 1–1 |
Ae. scutellaris | 1.75 | 9 | 1 | 214 | 0 | 0.9 | 1 | 0.9 | 1 | 0.90 | 0.77–1 |
Ae. aegypti | 1.77 | 18 | 1 | 205 | 0 | 0.97 | 1 | 0.95 | 1 | 0.97 | 0.92–1 |
Ae. notoscriptus | 1.75 | 19 | 0 | 205 | 0 | 1 | 1 | 1 | 1 | 1 | 1–1 |
Ae. vigilax | 1.57 | 17 | 3 | 204 | 0 | 0.85 | 1 | 0.85 | 1 | 0.85 | 0.75–0.96 |
Ae. vexans | 1.57 | 16 | 4 | 204 | 0 | 0.8 | 1 | 0.80 | 1 | 0.85 | 0.75–0.96 |
Cx. quinquefasciatus | 1.79 | 29 | 1 | 190 | 4 | 0.97 | 0.98 | 0.97 | 0.98 | 0.97 | 0.92–1 |
Cx. iyengari | 1.77 | 18 | 0 | 205 | 1 | 1 | 0.99 | 1 | 0.99 | 0.99 | 0.99–1 |
Cx. sitiens | 1.64 | 20 | 0 | 214 | 0 | 1 | 1 | 1 | 1 | 1 | 1–1 |
Cx. annulirostris | 1.78 | 29 | 1 | 190 | 4 | 0.97 | 0.98 | 0.97 | 0.98 | 0.99 | 0.97–1 |
T. melanesiensis | 1.7 | 20 | 0 | 204 | 0 | 1 | 1 | 1 | 1 | 1 | 1–1 |
Six speciesa | 1.70 | 109 | 8 | 100 | 7 | 0.93 | 0.93 | 0.93 | 0.93 | 0.94 | 0.91–0.97 |
Five speciesb | 1.63 | 101 | 6 | 110 | 7 | 0.94 | 0.95 | 0.94 | 0.94 | 0.96 | 0.94–0.99 |