Fig. 3

KEGG pathways enriched from DEG in macrophages inoculated with N. caninum versus non-infected cells. The graph shows the KEGG pathways [86] enriched from DEG of bovine macrophages infected for 8 h with N. caninum Nc-Spain7 (MØ7), Nc-Spain1H (MØ1H), and inoculated with heat-killed tachyzoites (MØHK) in relation to non-infected cells. The x-axis represents the number of DEG mapped for each pathway. Dark bars indicate upregulated genes and light bars downregulated genes. Asterisks indicate pathways enriched with a Padj ≤ 0.05, considered statistically significant. Results were obtained from three biological replicates for each condition