Fig. 4

rHcADRM1 stimuli altered T cells cytokine secretion profiles in vitro. Goat T cells were stimulated with or without rHcADRM1 proteins for 24 h. The secretions of IL-2 (a), IL-4 (b), IL-10 (c), IL-17A (d), IFN-γ (e) and TGF-β1 (f) in the culture supernatant were determined by ELISA. Data are presented as minimum to maximum (all points). Asterisks denote statistically significant differences (*P < 0.05, **P < 0.01) compared with the control group. Three independent experiments were performed