Fig. 6

a The mRNA expression of Gal-1, Gal-3, IFNγ, IL-1β, IL-6, iNOS, and Ym1 detected by using qRT-PCR in the liver, spleen, and peritoneal macrophages of different groups of mice on day 22 after T. spiralis infection and/or on day 13 after PbANKA infection. Data are presented as the mean ± SD (n = 6 per group). *P < 0.05, **P < 0.01, and ***P < 0.001 vs naive mice; ⁺⁺⁺P < 0.001 vs T. spiralis-mono-infected mice; ^#P < 0.05, ^##P < 0.01, and ^###P < 0.001 vs PbANKA-mono-infected mice. b Significant correlations were found between Gal-3 and IL-1β in the peritoneal macrophages from PbANKA-mono-infected mice, between Gal-3 and IFNγ in the spleen of T. spiralis + PbANKA-co-infected mice, and between Gal-1 and Ym1 in the peritoneal macrophages from co-infected mice. Data are expressed as the mean ± SD (n = 6 per group). The r value generates the theoretical line of best fit, and the P-value indicates the significance of the correlation