Fig. 2

Phylogenetic analysis of conserved TNFR domains of platyhelminth TNFRs. The regions containing four TNFR domains of platyhelminth receptor homologs were used to perform an alignment using MUSCLE. Bayesian inference was used to construct a phylogenetic tree using MrBayes. Clade credibility values are indicated on the left, close to each branch. On the right side, the order and class of each species and the status of DD conservation are represented (red pentagon represents conserved DD, dark gray pentagon with red border represents region with strong evidence of DD; light gray pentagon with dark gray borders represents weak evidence of DD)