Fig. 1

Histopathological changes in the intestine during the early phase of infection by T. spiralis. Hematoxylin and eosin staining (a, b, e) and Hematoxylin/Alcyan Blue-PAS staining (c, d). Sections from non-infected (a) and infected rat small intestine showing villi atrophy (b), goblet cell hyperplasia and mucus hypersecretion (d) surrounding the parasite in the intestinal lumen (c, white arrow) and intestinal mucosae damage caused by the AW (d, black arrow). a–d original magnification 10×; e and f original magnification 20×; a is normal rat intestine while b–f are from rat intestine on 6 dpi. Scale-bars: a, b, e, f, 100 µm; c, d, 50 µm