| Kato-Katz | qPCR 1st Follow-up sample | qPCR 1st and 2nd Follow-up samples | ||||||
---|---|---|---|---|---|---|---|---|---|
 | ALB | IVM-ALB | P-valuea | ALB | IVM-ALB | P-valuea | ALB | IVM-ALB | P-valuea |
T. trichiura | |||||||||
 No. cured/No. positive BL | 10/160 | 75/160 |  | 8/150 | 55/151 |  | 8/150 | 35/151 |  |
 Cure rates, % (95% CI) | 6.3 (3.0–11.2) | 46.8 (39.7–55.9) |  | 13.3 (8.3–19.8) | 36.4 (28.8–44.6) |  | 5.3 (2.3–10.2) | 23.2 (16.7–30.7) |  |
 ORcure (95% CI) | 1 | 13.7 (6.7–28.0) | < 0.001 | 1 | 3.7 (2.1–6.6) | < 0.001 | 1 | 5.4 (2.4–12.0) | < 0.001 |
A. lumbricoides | |||||||||
 No. cured/No. positive BL | 38/40 | 47/47 |  | 64/71 | 66/77 |  | 55/71 | 58/77 |  |
 Cure rates, % (95% CI) | 95 (83.1–99.4) | 100 (92.5–100) |  | 90.1 (80.7–95.9) | 85.7 (75.9–92.6) |  | 77.5 (66.0–86.5) | 75.3 (64.2–84.4) |  |
 ORcure (95% CI) | 1 | NA (0.62, –>) | 0.21 | 1 | 0.6 (0.2–1.8) | 0.41 | 1 | 0.6 (0.2–1.3) | 0.76 |
Hookworm | |||||||||
 No. cured/No. positive BL | 22/30 | 18/23 |  | 32/42 | 30/42 |  | 28/42 | 22/42 |  |
 Cure rates, % (95% CI) | 73.3 (54.1–87.7) | 78.3 (56.3–92.5) |  | 76.2 (60.5–87.9) | 71.4 (55.4–84.3) |  | 66.7 (50.5–80.4) | 52.4 (36.4–68.0) |  |
 ORcure (95% CI) | 1 | 1.3 (0.4–4.7) | 0.68 | 1 | 0.8 (0.3–2.0) | 0.62 | 1 | 0.9 (0.4–1.9) | 0.184 |