Ketamine can be produced by Pochonia chlamydosporia: an old molecule and a new anthelmintic?

Parasites & Vectors

Table 2 Activity of P. chlamydosporia extracts on C. elegans larvae

Extract	Immobility (%) [concentration of 1000 and 5000 µg/ml]
Extract	Time: 48 h	ED₅₀ (µg/ml)
EtOAC	84.0	325.3
CH₂Cl₂	55.5	1400
MeOH	66.9	3365

Notes: CH₂Cl₂ and MeOH were tested at concentrations of 5000 µg/ml because we did not find an effective dose (ED₅₀) in the test with a concentration of 1000 µg/ml. We evaluated the motility of larvae 48 h after contact with the extract

ISSN: 1756-3305